Hormone Drugs
Pharmacy Tech
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- Synthesized in various tissue types.
- Released and act locally
- Act throughout the body
- Poduced by one specific tissue (gland)
- Exert profound changes in the body
- Have a regulatory effect
- Found in all tissues of the body; causes bronchial constriction, stomach acid secretion, blood vessel dilation, and local edema (swelling), pain, and itching
- A group of local hormones that cause a variety of local reactions, cause uterine and bronchial contractions and relaxation, decreased gastric secretions, pain, and inflammation
- Treatment of allergies, rashes, and hay fever • Motion sickness, nausea, and dizziness • H2 antagonist is used to treat ulcers and reflux disease Mechanism of Action • Inhibits the action of histamine
- Competitively antagonize histamine at the H1 receptor (block histamine). They cross the blood brain barrier making them a CNS drug.
- Do not cross blood brain barrier, no sedation
- Blocks chemicals produced by the body called leukotrienes (hormone-like substances that cause allergy symptoms). Leukotrienes cause the lining of the breathing passages of the lung to swell.
- A group of drugs whose main action is a long-lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available today.
- Use • Nausea/vomiting • GERD Mechanism of Action • Improves stomach emptying
- Uses • Arthritis • Minor pain • Fever • Inflammation Mechanism of Action • Inhibit or reverse the actions of prostaglandins by blocking Cox-1 and Cox-2 enzymes
- Use • Glaucoma: decrease intraocular pressure Mechanism of Action • Increasing the outflow of aqueous fluid from the eyes
- Uses • NSAID ulcer prevention • Abortifacient (abortion)
- Male hormones, which are secreted by the testes, are responsible for the characteristic sexual changes in men (sexual organ development, hair growth, muscle development, and deepening of the voice).
- Female hormones, which are secreted by the ovaries, are also responsible for development of female sexual characteristics (breast development, body fat distribution, sexual organ development, and menstruation).
- Female hormones secreted by the corpus luteum also cause growth of mammary ducts and prevention of uterine bleeding during pregnancy.
- Are drugs that act both to prevent ovulation or fertilization and possibly post-fertilization implantation of a blastocyst (embryo). ECPs are distinct from medical abortion methods that act after implantation.
- Hormones secreted by the adrenal gland
- Hormone produced by pancreas by the Beta cells • To replace _____ in patients with Type I or Type II diabetes Mechanism of Action • Facilitates the utilization and storage of glucose
- Patient who does not produce any insulin and requires daily insulin injections for survival
- Patient who produces some insulin, but generally not enough to allow proper glucose utilization.
- Hormones secreted by the pituitary, which stimulate the contraction of uterine smooth muscle Uses • Relief from breast enlargement during lactation and control of postpartum uterine bleeding
- Manage patients with Type II diabetes
- To treat over secretion of thyroid hormones (hyperthyroidism)
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