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Suppositories

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Dosage Form suppositories quiz

SaharHaydar
Created Date 03.15.22
Last Updated 03.16.22
Viewed 0 Times
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  • Systemic rectal suppository used for the relief of nausea and vomitting
  • Opioid analgesic
  • Relief of migraine suppositories
  • Can be avoided if suppository is not inserted too high
  • Neutral body fluid that lack any effective buffering capacity
  • Suppository base that melts rapidly at body temperature, and immiscible with rectal fluid
  • The form in which drug should be incorporated when using cocoa butter as base for fatty drugs
  • When distributed in a fatty suppository base in low concentrations it has less tendency to escape to the surrounding aqueous fluids than a hydrophilic
  • It should remain solid at room temperature but soften melt or dissolve readily at room temperature
  • Fat soluble drugs are more readily released from this type of suppository bases
  • Metastable crystalline form alpha crystals of cocoa butter, with lower than usual melting point
  • Substance with a tendency to lower the melting point of cocoa butter
  • 20% granular gelatin with 70% glycerin
  • 60% gelatin with 20% glycerin
  • Suppository base that does not melt at body temperature but mix with mucous secretions upon dissolution