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CNS, Renal, & Genetic/Bone Marrow Effects

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PLAAAY BALLL!!!

cleoespinoza
Created Date 04.14.19
Last Updated 04.15.19
Viewed 13 Times
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Topics of this game:
  • Which volatile agent does NOT decrease the cerebral metabolic rate?
  • You are administering anesthesia to a patient undergoing surgery for an intracranial mass. Which IA should you use at 0.8 MAC or less to help keep the intracranial pressure from increasing?
  • Which IA is implicated in the production of compound A?
  • Which IA is most commonly implicated in the increased risk of spontaneous abortions among operating room personnel?
  • Fluoride and compound A are two potential byproducts of which IA administration?
  • Which IA is unique in that its low blood/gas solubility facilitates a rapid emergence, which may be useful for immediate postoperative neurologic evaluation?
  • Which IA is unique in its ability to INCREASE CSF secretion?
  • Due to the production of compound A, what is the minimum recommend fresh gas flow rate for Sevoflurane?
  • Which IA is considered to offer cerebral protection against necrotic processes secondary to ischemic events during a carotid endarterectomy?
  • Does Isoflurane, N2O, Desflurane, or Sevoflurane have a HIGHER dose-dependent cerebral vasodilatory effect?
  • Do IAs cause increased or decreased renal vascular resistance?
  • Prolonged administration of which IA can produce megaloblastic changes in bone marrow due to interference in the activity of Vitamin B12-dependent enzymes?
  • You prep your anesthesia machine for the first case on Monday morning and notice the oxygen was left on. Your patient is otherwise healthy. The case is long, you need a coffee, and to top it off the machine reads persistently but only slightly elevated EtCO2 readings. Postoperatively the patient experiences diuresis, glycosuria, proteinuria, and increased serum BUN and creatinine levels. What do you expect occurred?
  • Does Sevoflurane, Isoflurane, or N2O disrupt vitamin B12 dependent enzymatic activity to the greatest degree?
  • In an effort to minimize N2O induced healthcare worker detriments, what are the OSHA recommended guidelines (in parts per million) of N2O exposure without concomitant use of a halogenated agent, based on a time-weighted 8-hour average concentration?
  • Does N2O or Isoflurane require a lower MAC value to prevent recall and response to commands?
  • Which IA not only does not evoke seizure activity, but also possesses anticonvulsant properties?
  • Given the high fluoride levels expected with Sevoflurane administration, would you expect your patient have impairment in their ability to concentrate urine?
  • Which enzyme, impaired by N2O, is responsible for converting homocysteine to methionine for myelin synthesis?
  • The Ames test on the all IA is negative. This means that these agents and their metabolites are not?
  • Which IA is contraindicated in a patient suspected of having a pneumocephalus or an air embolism?
  • Which IA induces the smallest degree of cerebral vasodilation and preserves cerebral autoregulation up to 1.5 MAC?
  • Megaloblastic changes in bone marrow are found in patients with N2O exposure of how many hours?
  • Which IA is unique in that it is the only agent to facilitate CSF absorption?
  • In prep, your patient read on Google that N2O has many potential adverse effects on bone marrow function and asks if its use during his bone marrow transplantation will affect his marrow viability. Is its use contraindicated in such an instance?
  • How are cerebral metabolic rate (CMRO2) and cerebral blood flow (CBF) altered by isoflurane?
  • Which inhalational anesthetic can suppress convulsive activity induced by lidocaine?