Menopause
pts with menopause
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Topics of this game:
- hx of irregular menses before perimenopause, AA heritage, cigarette smoking, & weight reduction diet
- CHD, stroke, hop fx, breast cancer, endometrial cancer, colorectal cancer, osteoporosis
- amenorrhea, vasomotor symptoms, genituourinary changes
- tx with estrogen & progestin in women with an intact uterus & estrogen in women w/out uterus
- HT with estrogen minimizes VMS & genitourinary symptoms related to estrogen deficiency
- Associated with a lower risk of venous thromboembolism compared to oral formulations
- Used at lowest effective dose and for shortest duration possible
- Known breast or endometrial cancer, untreated endometrial hyperplasia, uncontrolled HTN
- Gallbladder disease, increase in serum triglycerides, breast cancer, thromboembolic disease
- Tx of moderate to severe dyspareunia
- Lacks increased risk of breast cancer due to antiestrogenic activity in breast tissue
- undiagnosed, abnormal vaginal bleeding, estrogen-dependent neoplasia, & hx of active thromboembolism
- Increased risk of VTE events, CVD, and endometrial cancer
- Bazedoxifene
- reduces risk for developing endometrial hyperplasia
- Tx of moderate to severe VMS
- Bazedoxifene estrogen agonist effect
- 4-8 wks to evaluate response
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